Programme: Sunday 20 April 2008

09:30 Registration and refreshments
   
10:45 Conference Opening and Keynote Session I
Chair: James Brown, University of Cambridge, UK
   
10:45 Welcome
Richard Kitney, Imperial College London, UK
   
11:00 Keynote Address 1 - Title to be confirmed
Tom Knight, Computer Science and Artificial Intelligence Lab, MIT
   
12:00 Keynote Address 2 - From Molecular Machines to Gene-Regulatory Networks in Mammalian Cells
Thomas Höfer, German Cancer Research Center, Heidelberg, Germany
   
13:00 Lunch
   
  Session 1 - Synthetic Biology
Chair: Jim Haseloff, University of Cambridge, UK
   
14:00 (1.1) Title to be advised
J Haseloff, University of Cambridge, UK
   
14:20

(1.2) Rational Design of a Set of Versatile Synthetic Biological Modules
B Wang, V Rouilly, R Kitney, Imperial College London, UK, C-L Poh, Nanyang Technological University, Singapore

   
14:45 (1.3) GenoCAD: A Formal Language Tool to Quickly Design and Verify Synthetic Genetic Constructs
Y Cai, J Peccoud, Virginia Bioinformatics Institute at Virginia Tech, USA, C Gustafsson, DNA2.0, Inc., USA
   
15:10 (1.4) Automatic Design Tools for Synthetic Biology
G Rodrigo, J Carrera, IBMCP-UPV Spain, M Suarez, A Jaramillo, École Polytechnique, France
   
15:35 (1.5) In Vitro Synthetic Oscillators
J Kim, CbsBioscience Inc., Republic of Korea, E Winfree, California Institute of Technology, USA
   
16:00 Refreshments
   
16:30 Session 2 - Bioinformatics & Computational Biology I
Chair: Jean Peccoud, Virginia Bioinformatics Institute at Virginia Tech, USA
   
16:30 (2.1) From Registries of Biological Parts to IDE of Genetic Systems
J Peccoud, Virginia Bioinformatics Institute at Virginia Tech, USA
   
17:15 (2.2) A Spatio-Temporal Algorithm for Resolving Time-Lapse Imaging of Bacteria
A Demarez, M Primet, F Taddei, A B Lindner, L Moisan, Paris Descartes University, France
   
17:40 (2.3) Transcription Factor Heterogeneity in Single Human Embryonic Stem Cells
M Hemberg, Children's Hospital Boston, USA, A Stahlberg, H Semb, Lund University, Sweden, M Bengtsson, Oxford University, UK, M Barahona, Imperial College London, UK
   
18:05 (2.4) Modelling the Endothelial Cell Response to Fluid Flow
R J Allen, I D L Bogle, University College London, UK, A J Ridley, King's College London, UK
   
18:30 Sponsors’ Reception and Poster Session
   
  Poster series 1 - Synthetic Biology
   
  P1.01 - Riboswitch Development: Design of in Vivo Circuits
N Kelley-Loughnane, S Harbaugh, Y Chushak, M O Stone, Applied Biotechnology Branch, Human Effectiveness Directorate, Air Force, USA
   
  P1.02 - The E. coli Integrated Network and the Self Contained Regulatory Loops
H Ma, I Goryanin, University of Edinburgh, UK
   
  P1.03 - Data Integration to Constrain Computational Modelling in Synthetic Biology
J S Hallinan, M Pocock, A Wipat, Newcastle University, UK
   
  P1.04 - Self-Assembly of Protein Amyloid
C F Lee, Oxford University, UK
   
  P1.05 - An RNAi-Enhanced Logic Circuit: Cancer-Specific Detection and Destruction
A Swaminathan, J Monk, P Cowgill, R Weiss, P Purnick, P Guye, Princeton University, USA
   
  P1.06 - YeSOil A Yeast Sensor for Real Extra Virgin Olive Oil
R Bergamasco, M Graziano, M A Ricci, G Russo, L Marucci, M di Bernardo, University of Naples Federico II, Italy, I Cantone, G Cuccato, V Siciliano, M P Cosma, D di Bernardo, TIGEM Telethon Institute of Genetics and Medicine, Italy
   
  P1.07 - Computational Design of Synthetic Molecular Clocks with Targeted Cell Growth
G Rodrigo, J Carrera, Instituto de Biologia Molecular y Celular de Plantas, CSIC-UPV, Spain, B Canton, D Endy, MIT, USA, A Jaramillo, École Polytechnique, France
   
  P1.08 - Biological Implementation of Algorithms
A Becerra, F Castro, L Martinez, Y Robles, F Ramirez, P Padilla, E Samra, University of Mexico (UNAM), Mexico, R Palma, Mexican Institute of Technology (IPN), Mexico
   
  P1.09 - Variety of Dynamics Regimes in Synthetic Genetic Oscillators
A Koseska, J Kurths, Potsdam University, Germany, A Zaikin, University of Essex, UK, J Garcia-Ojalvo, Universitat Politecnica e Catalunya, Spain, E Volkov, Lebedev Physical Institute, Russia
   
  Poster series 2 - Bioinformatics & Computational Biology
   
  P2.01 - Molecular and Comparative Modelling and Docking Analysis of CDC4 Proteinin Homo sapiens
A Khanzode, PT. Ravishankar Shukla University, India
   
  P2.02 - Identifying the Features of co-translational Protein Folding
R J K Saunders, C M Deane, University of Oxford, UK
   
  P2.03 - Use of Virtual Environments and Selection of Measurement Parameters for the Application in the Phobia Treatment
M Plaza, Universidad Libre, Colombia
   
  P2.04 - ConFunc - Functional Annotation in the Twilight Zone
M N Wass, M J E Sternberg, Imperial College London, UK
   
  P2.05 - Development of an Extensible System for the Capture and Storage of Experimental Enzyme Kinetics Data
N Swainston, K Smallbone, F Khan, H L Messiha, I Spasic, D B Kell, University of Manchester, UK, M Golebiewski, S Mir, I Rojas, EML Research, Germany
   
  P2.06 - Morphogenesis in Cellular Automata Models of Non-Linear Media
G Juarez Martinez, P Padilla Longoria, University of the West of England, UK
   
  P2.07 - Hierarchy, Abstraction Levels and Emergent Behaviours in Agent-based Simulations of Complex Biological Systems
C C Chen, University College London, UK
   
  P2.08 - NetBuilder’ - Evolving Genetic Regulatory Networks
K Wegner, J F Knabe, C L Nehaniv, M J Schilstra, University of Hertfordshire, UK
   
  P2.09 - Software Development in Modelling and Virtual Exploration of Proteins: an Alternative of IT in Central America
A Orozco, UNA, Costa Rica
   
  P2.10 - Predicting the Function of the Protein-Tristetraproline
N Pillai, A Kumar, Deemed, India
   
  P2.11 - A Process Model of Actin Polymerisation
O Kahramanogullari, E Caron, P Gardner, Imperial College London, UK, L Cardelli, Microsoft Research, UK
   
  P2.12 - Protein Network Alignment for Functional and Structural Annotation
W Ali, C Deane, Oxford University, UK
   
  P2.13 - Improving Loop Prediction by Improving Loop Selection
Y J Choi, C Deane, Oxford University, UK
   
  P2.14 - Environment-Specific Substitution Tables for Membrane Proteins
S Kelm, C M Deane, University of Oxford, UK, J Shi, UCB Celltech Ltd, UK
   
  P2.15 - Quantitative PCR Primer Database for Terpene Synthesizing Genes in Selected Aromatic Plants
M Pattanayak, S K Gupta, F N Jaffery, Industrial Toxicology Research Centre, India
   
  P2.16 - Error Tolerance of Gene Networks and their Robustness to Different Timescales
S Yeniterzi, C Atilgan, A R Atilgan, Sabanci University, Turkey
   
  P2.17 - The Determination of the Basis of HLA Class I Associated Protection in HTLV-I Infection
A MacNamara, B Asquith, C Bangham, Imperial College London, UK
   
  P2.18 - HIV-1 Escape from Cytotoxic T-Lymphocytes in Gag, but not in Other Genes, is Detrimental to the Host
U Kadolsky, B Asquith, Imperial College London, UK
   
  P2.19 - A General Model for Inferring Boolean Networks from Sparse Gene Expression Data
L Yu, S Marshall, University of Strathclyde, UK, P Ghazal, S Watterson, University of Edinburgh, UK
   
  P2.20 - Statistical Analysis of Time Series of Gene Expression Response to Mycobacterium tuberculosis Infection
M Berk, G Montana, Imperial College London, UK
   
  P2.21 - Evolution of the G+C Content Frontier in the Rat Cytomegalovirus Genome, and its Effect on Gene Length
D Gatherer, MRC Virology Unit, UK
   
  P2.22 - A New Approach to Calculate the Measure of Similarity of 3D Structures in Proteins
R Yeniterzi, S Yeniterzi, A Kucukural, U Sezerman, Sabanci University, Turkey
   
  P2.23 - GeneTrail - Statistical Evaluation and Visualization of Biological Pathways
C B Backes, A C K Keller, J K Küntzer, H P L Lenhof, Saarland University Germany, A G Gerasch, M K Kaufmann, Eberhard Karls University, Germany
   
  P2.24 - Predicting and Understanding Gene Interaction Networks based on Sequence Information
F Schubert, V Pancaldi, J Bahler, Wellcome Trust Sanger Institute, UK
  
  P2.25 - Prediction of Glycosylation Sites using Random Forests
S E Hamby, J D Hirst, University of Nottingham, UK
  
  P2.26 - Selection of Algal Strain by Sequence Analysis for Biodiesel
N Pillai, A Kumar, Deemed, India
  
  P2.27 - Placental Malaria in Different HLA Alleles
P B Karau, University of Nairobi, Kenya
  
  P2.28 - Making Sense of Microarray Gene Lists using Text Mining and Over-Representation Analysis
H S Leong, P Giles, S Menon, D Kipling, Cardiff University, UK
  
  P2.29 - Spatial Knowledge Retrieval and Discovery in Chromosomes
A Martin Pittock, University of Edinburgh, UK
  
  P2.30 - Semi Supervised Spectral Clustering for Regulatory Module Discovery
A Mishra, D Gillies, Imperial College London, UK
  
  P2.31 - Biomarker Discovery using Genetic Algorithms
A Küçükural, D Yörükoğlu, U Sezerman, Sabanci University, Turkey
  
  P2.32 - Synthetic Cis-Regulatory Bio-Logic Gates in Escherichia Coli
Z Jian, Z Yun, H Y Liu, University of Science and Technology of China, China
  
  P2.33 - Using Annotation for the Integration and Interpretation of Microarray Data
S Menon, P Giles, I Brewis, H S Leong, D Kipling, Cardiff University, UK
  
  Poster series 3 - iGEM
   
  P3.01 - Promoter Calibrator: One Possible Application for a Biological Comparator
P Aparicio, O Cuenca, J Garzon, R Soriano, A Ferrando, J Pereto, Universidad de Valencia, Spain, D Das, S K Maiti, A Montagud, H Mosquera, M Baguena, E Navarro, P Fernandez-de-Cordoba, J Urchueguia, Universidad Politécnica de Valencia, Spain, A Jaramillo, École Polytechnique, France
   
  P3.02 - ElectrEcoBlu: A Novel Self-Powering Electrochemical Biosensor
X Gu, S Ramsay, D Gilbert, University of Glasgow, UK
   
  P3.03 - University of Edinburgh iGEM 2007 Projects: A Cell Division Detector, and Self-Flavouring Yoghurt
C Dahl, L Gerosa, S Hollingshead, A Marshall, P Ravindranath, J Rokicki, X Wang, D Yin, A Elfick, C French, H Ma, University of Edinburgh, UK
   
  Poster series 4 - Systems Biology
   
  P4.01 - Comparative Study of Mathematical Models for Gene Regulatory Networks
A Polynikis, M di Bernardo, S J Hogan, University of Bristol, UK
   
  P4.02 - Systematically Identifying the Key Controllers of Growth Rate in a Eukaryotic Cell
K Gkargkas, S G Oliver, University of Cambridge, UK
   
  P4.03 - Cold Glycerol-Saline: The Promising Quenching Solution for Accurate Intracellular Metabolite Analysis of Microbial Cells
S G Villas-Boas, P Bruheim, University of Auckland, New Zealand
   
  P4.04 - Dynamic Transcription Modelling Identifies Gene Networks using Time Course Expression Data and Transcript Turnover Rates
M Barenco, E Papouli, M Hubank, University College London, UK, D Brewer, Institute of Cancer Research, UK, J Stark, Imperial College London, UK
   
  P4.05 - Evolution of Evolvability in Gene Regulation Networks
A B M Crombach, P Hogeweg, Utrecht University, Netherlands
   
  P4.06 - Glycomic Analysis of O-Gycosylation in Knockout Mice
M N Ismail, M Panico, S Haslam, A Dell, Imperial College London, UK
   
  P4.07 - Gene Regulatory Network Inference in the Fission Yeast Schizosaccharomyces Pombe
S D Kane, F Schubert, L Maury, Wellcome Trust Sanger Institute, UK
   
  P4.08 - Reconstraction of Saccharomyces Cerevisiae and Schizosaccharomyces Pombe Metabolic Pathways Base on Enzyme Nomenclature Database
K-Y Lo, A Dalby, University of Oxford, UK
   
  P4.09 - Model Discrimination and Robustness for Cyanobacterial Circadian Oscillators
M Hafner, H Koeppl, École Polytechnique Fédérale de Lausanne, Switzerland, A Wagner, University of Zurich, Switzerland
   
  P4.10 - Bottlenecks in Escherichia Coli-based Glyoxylate Production Revealed by 13C-Flux Analysis
S Noack, M Kunze, K Nöh, Research Centre Jülich, Institute of Biotechnology, Germany
   
  P4.11 - Robust Stability of Metabolic Networks
H Koeppl, M Hafner, École Polytechnique Federale de Lausanne (EPFL), Switzerland, A Wagner, University of Zurich, Switzerland
   
  P4.12 - Modelling the IP3 / Calcineurin / NFAT Pathway in the Cardiac Myocyte
M T Cooling, P J Hunter, E J Crampin, University of Auckland, New Zealand
   
  P4.13 - Understanding Chemotaxis in R. Sphaeroides
M A J Roberts, E August, J P Armitage, P McSharry, P K Maini, A Papachristodoulou, University of Oxford, UK
   
  P4.14 - Diffusion Simulation of Protein Molecules through the Cytoplasm of Escherichia Coli
Y D Yu, Y J Choi, A Dalby, University of Oxford, UK
   
  P4.15 - Modelling of Methylglyoxal Detoxification in Bacteria
C Almeida, E Ozyamak, I R Booth, C Grebogi, A Moura, University of Aberdeen, UK
   
  P4.16 - Bridging the Gap between Constraint-based and Kinetic Modelling
K Smallbone, E Simeonidis, D S Broomhead, D B Kell, Manchester Centre for Integrative Systems Biology, UK
   
  P4.17 - From QconCAT to Molecules per Cell: Accurate Quantification of Absolute Enzyme Concentrations in Yeast by Mass Spectrometry
K M Carroll, D Simpson, C E Eyers, C Knight, S J Gaskellm, R J Beynon, D B Kell, University of Manchester, UK
   
  P4.18 - Stochastic Parameter Estimation using Minimum Entropy: Application to the RKIP Regulated ERK Signalling Pathway
G Papadopoulos, M Brown, University of Manchester, UK
   
  P4.19 - Information-Theoretic Analysis for Exploring Death-Survival Signalling in Glioblastoma
Y C Tang, Singapore-MIT Alliance, Singapore, G Stephanopoulos, Massachusetts Institute of Technology, USA, H-P Too, National University of Singapore, Singapore
   
  P4.20 - Global Sensitivity Methods for Identifiability Analysis and Model Reformulation in Systems Biology
M Rodriguez-Fernandez, J R Banga, IIM-CSIC, Spain, A Kremling, Max-Planck-Institute for Complex Technical Systems, Germany
   
  P4.21 - Inference and Modelling of Regulatory Networks from Transcriptomic Data
J Carrera, G Rodrigo, Instituto de Biologia Molecular y Celular de Plantas, CSIC-UPV, Spain, A Jaramillo, École Polytechnique, France
   
  P4.22 - An Accelerated Algorithm for the 3D Poisson-Nernst-Planck Calculations of Ion Fux through Membrane Channels
W W Dyrka, M Kotulska, Wroclaw University of Technology, Poland, A T Augousti, Kingston University, UK
   
  P4.23 - Parameter Estimation for Gene and Protein Interaction Networks
R K Shelton, W T Baumann, Virginia Polytechnic Institute and State University, USA, J Peccoud, Virginia Bioinformatics Institute at Virginia Tech, USA
   
  P4.24 - Biochemical Reaction Kinetic Parameters Identification by means of Evolutionary Algorithms: Application to EGFR Pathway
F Menolascina, G Bevilacqua, D Naso, G Mastronardi, Polytechnic of Bari, Italy
   
  P4.25 - Integrated Statistical and Optimization Analysis of Nonlinear Systems with Noisy and Sparse Data, an Application to Biochemical Pathways
X Gu, M Barrett, D Gilbert, University of Glasgow, UK
   

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